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KMID : 0363619970180010326
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Journal of Korean Oriental Medicine
1997 Volume.18 No. 1 p.326 ~ p.336
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Effects of aqua-acupuncture with Panax Ginseng on immune response induced by Glucocorticoid in mouse
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Lee Eun-Hong
Lim Jong-Kook
Moon Jin-Young
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Abstract
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In order to investigate the effect of aqua-acupuncture solution with Panax Ginseng into Qihai(CV_6) and Shenshu(BL_{23}) on immune response induced by glucocorticoid in mouse, Panax Ginseng aqua-acupuncture solution was injected into Qihai(CV_6) and Shenshu(BL_{23}) for seven days after injection with glucocorticoid. And then MA-HRP (methamphetamine-horseradish peroxidase) induced antibody production, numbers and lysozyme activity in macrophage were measured. The results were as follows: 1. The antibody production in mouse immunized with MA-HRP was decreased in control group as compared with normal group. Although Qihai(CV_6) group showed slight increasement, Shenshu(BL_{23}) group indicated great increasement compared with normal group. However in Aa-BL group, antibody production was almost increased to normal group. 2. In control group, the numbers of macrophage were decreased about 14% as compared with normal group. And in the pretreated groups of Qihai(CV_6) and Shenshu(BL_{23}) were respectively increased 3.0 times and 2.9 times as compared with normal group. 3. Effect of Panax Ginseng-aqua acupuncture solution on the lysozyme activity in macrophage was increased gradually in the pretreated groups of Qihai(CV_6) and Shenshu(BL_{23}) as compared with control group. These results suggest that Panax Ginseng aqua-acupuncture at Qihai(CV_6) and Shenshu(BL_{23}) may increase antibody production and lysozyme activity in macrophage that is suppressed by glucocorticoid, and Panax Ginseng aqua-acupuncture will have immuno adjuvant effects on the cells which concerned with immunomechanisms.
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KEYWORD
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